Endocrine Abstracts

Introduction: Non-functioning adrenal incidentaloma (NFAI) is a frequently diagnosed since the increased use of radiological examinations. The recent studies have shown that NFAI might have negative cardiometabolic effects and increased cardiovascular risk. The aim of this case control study was to determine the relationship between NFAI, CRP-hs, uric acid and cardiovascular risk (CVR) based on GLOBORISK algorithm of Tunisia.Methods: This case-control st...

Introduction: Vitamin D deficiency is an emerging concern that has the potential to impact one’s health, even in sunny Mediterranean countries like Tunisia. This issue is particularly notable among indoor workers in the healthcare sector, who experience minimal sun exposure. The aim of this study was to describe the Vitamin D profile within this specific population and to establish its association with lipid parameters.Methods: This cross-sectional ...

Introduction: Cushing’s syndrome (CS) has relevant morbidity and mortality and poses several diagnostic challenges underlining the need for a prompt diagnosis in order to initiate earlier treatment. The aim of the present study was to develop a new clinical and biological score to predict the diagnosis of CS.Methods: This was a monocentric retrospective study including patients who were admitted to the Department of Endocrinology of La Rabta Hospita...

Introduction: The prevalence of metabolic syndrome (MS) is constantly increasing, particularly among young individuals with sedentary professions. Identifying individuals with MS is crucial for implementing personalized interventions to prevent cardiovascular events. Our study aimed to assess the metabolic profile of young and healthy healthcare professionals, considering the specific lifestyle linked with their professional roles.Methods: This cross-sec...

Introduction: The 1-mg overnight low-dose dexamethasone suppression test (DST) has been used to screen for mild autonomous cortisol secretion and Cushing’s syndrome (CS). The aim of the present study was to determine the DST discriminatory threshold confirming the diagnosis of CS.Methods: This was a monocentric retrospective study including patients who were admitted to the Department of Endocrinology of La Rabta Hospital, Tunis between 2014 and 202...

Introduction: Adrenal incidentalomas (AI) are adrenal masses detected on imaging performed for reasons other than suspected adrenal disease. It is important to categorize whether the mass is a functioning or non-functioning incidentalomas to determine the appropriate management and follow-up. The aim of this study was to assess demographic, clinical, and paraclinical features of patients with AI.Methods: This was a monocentric retrospective study includi...

Introduction: DiGeorge syndrome (DGS) is mainly characterized by congenital heart defects, dysmorphic features, hopolasia of the thymus and parathyroid glands and immunodeficiency. Approximately 10% of patients with DGS have autoimmune disease1. Observation: This is a 21-year-old patient, diagnosed with DGS at the age of 14 year old. The diagnosis was suspected on the association of characteristic facial, hypoparathyroidism and a congenital he...

Introduction: Insulinomas are rare pancreatic endocrine tumors causing severe hypoglycemia in non-diabetic patients. We report a case of a rare association between insulinoma and type 2 diabetes.Presentation of the case: A 65-year-old diabetic patient presented with a one year history of recurrent hypoglycemia even after the withdrawal of antidiabetic drugs. First, a functional hypoglycemia was suspected and an oral glucose tolerance test showed hypoglyc...

Introduction: Sheehan’s syndrome is a rare cause of hypopituitarism. It is defined by an ischemic necrosis of the pituitary gland following postpartum hemorrhage. Sheehan syndrome is characterized by various endocrine deficiencies. The aim of the present study was to determine the clinical and paraclinical characteristics of women with Sheehan syndrome.Methods: This was a monocentric cross-sectional study including 50 women followed for Sheehan&#146...

Introduction: Pheochromocytoma is a rare tumor originating from chromaffin cells of the adrenal medulla secreting catecholamines. The typical symptoms of pheochromocytoma include hypertension, headache, heart palpitations, anxiety, and profuse sweating. However, some patients with pheochromocytomas remain asymptomatic. The aim of this study was to determine the clinical and paraclinical characteristics of incidentally discovered pheochromocytomas.Methods...